(A) Southern blot analysis of the leukemia cell sample derived from t(1;11)(q23;p15) AML. Genomic DNA samples from the t(7;11)(p15;p15) AML patient as well as healthy control were also shown. Rearranged bands were detected both in t(1;11) patient as well as t(7;11) by Sac I digestion using a NUP98 probe. (B) 3′-RACE products of NUP98 fusion cDNA. MWM, 123-bp ladder molecular weight marker; RT(+), reverse transcribed and PCR-amplified patient poly(A)⁺ RNA sample; RT(−), patient RNA without reverse transcription. (C) Southern blot analysis of the patient genomic DNA with the 3′-fragment of shorter RACE product as a probe. Rearranged band was detected in patient sample digested withBamHI.