Cell proliferation in normal, deficient, and deficient transduced (LXSN or LUDSN11) and selected LB cell lines. Assays were performed at different time intervals (0 to 72 hours) with the LB44 (A), LB45 (B), and LB86 (C) cell lines. For each cell line, results are shown for nontransduced (•), LXSN-transduced (□), and LUDSN-transduced cells (▪). As a reference, a normal LB cell line is also shown (○). Determination was performed by the CellTiter 96^rAQueous Solution Cell Proliferation Assay (Promega Corp; MTS test). Results of experiments for each cell line were the mean of five determinations from three independent experiments. * P < .05, **P < .01 v the LBHEP/LUDSN11 cells.