IAP physically associates with 2β1 integrin. Platelets were lysed in 30 mmol/L octyl-β-D-glucoside and lysates were subjected to immunoprecipitation using mIgG and antibodies against 2, β1, and IAP. After sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), immunoblots were probed with 2 and β1 antibodies.