Relation between the in vitro drug resistance to DNR and etoposide together (a and b) or the simultaneous effect of both CsA and probenecid on calcein-AM uptake (b and d) and the probability (which analyzed the combined activity of Pgp and MRP1) of RFS and OS in untreated de novo AML patients. †Compared by the log-rank test; ††compared by the BreslowGehan-Wilcoxon test.