Effects of HOXA5 overexpression in CD34⁺CD38⁻ cells. (A) CD11b and (B) glycophorin expression from 4-week-old cultures of CD34⁺CD38⁻ cells transduced with eitherHOXA5 or control vectors (n = 6 independent experiments). (C) The effect of HOXA5 expression on CD11b and glycophorin expression is greater when CD34⁺CD38⁻ cells are transduced than when CD34⁺ cells are transduced (P = .006). Shown are the mean ± SEM of the increase in the percentage of CD11b⁺ cells (% HOXA5 − % control) and the decrease in the percentage of glycophorin⁺ cells (% control − % HOXA5; n = 6 CD34⁺CD38⁻ experiments and n = 15 CD34⁺ experiments).