Fig. 8.
Influence of KM81 MoAb on cytokine production by macrophages upon HA treatment. BMDM were treated with HA (100 μg/mL) for the times indicated either in the presence or absence of F(ab′)2 fragments of the pan CD44 antibody KM81 (20 μg/mL). The concentration of IL-6 (A) and IL-1β (B) was determined in the supernatant by ELISA. SE was calculated from results obtained from 3 independent wells each.
