Effect of PF-4–derived peptides on endothelial cell proliferation. (A) ACE cells or (B) LEII cells are incubated in DMEM containing 1% bovine serum (FCS for LEII cells and NCS for ACE cells) with or without 10 ng/mL FGF-2 and 10 μmol/L PF-4–derived peptides. 1% serum without FGF-2 (⧫), 1% serum with FGF-2 (•), 1% serum with FGF-2 and peptide 47-70 (▪), 1% serum with FGF-2 and peptide 34-58 (▴). Cells are counted every other day. (C) ACE cells or (D) LEII cells are incubated with 10 ng/mL FGF-2 and 10 μmol/L of various peptides and counted after 6 days.