Phylogenetic trees showing the relationship between the predicted protein encoded by Bm-spn-2 and all other recorded invertebrate serpins. Numbers above branches show the percentage of bootstrap support for each clade. GenBank, Protein Identification Resource, and SWISS-PROT accession numbers of the sequences used were as follows: T tridentatus intracellular coagulation inhibitor 2, A55533; T tridentatus intracellular coagulation inhibitor,D14483; Bm-spn-1 (Bm-SERPIN), U04206; Ce-spn (C elegansserpin), U50301; B mori antitrypsin, D00738; B moriantichymotrypsin II, P80034; M sexta serpin-1, U58361; M sexta serpin-2, U79184; B mori antichymotrypsin, D13895;P leniusculus proteinase inhibitor II, X82642;Bm-spn-2, AF009825.