Fig. 1.
![Fig. 1. Effect of retinoic acid on DNA synthesis. Human B cells were isolated and stimulated with μ (37.5 μg/mL) and SAC (0.005%) as described in Material and Methods. Cells (0.75 × 106 cells/mL) were cultured in 96-well culture plates in triplicates. Retinoic acid (10 or 1000 nmol/L) was added at the indicated times (T) after stimulation. [3H]Thymidine incorporation (mean ± SD) was measured as described in Material and Methods. One representative experiment of three is shown. μ, F(ab′)2 fragment of rabbit antihuman IgM; SAC,Staphylococcus aureus crude cell suspension; RA, retinoic acid.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/94/4/10.1182_blood.v94.4.1348/4/blod41629001x.jpeg?Expires=1735548043&Signature=f98dtpl75RzVHOAEqO6o-nyo6xYO88C5u9WqorN-~sLRv9pi9IANJJ4rvco0V6OYm2O1m7rr1DJm89DhG7bOtLgP9J-RTJmkW-meAmTT2NgxyAgpf169wIJkdEZQWhgyQ-ApyiUSvzcEZpXLNNK9cNyBWhlTc9q5lG65nrkwb2-m6WXDv6xl4a~8tGABgqwLwRxk3oiej~seG1PYQ41VCEuJhXWkLAC-Tv5r4ZALlHM3UyMDp0tpIxm-cvH9uJ8eXQJ5pSsA8R1DmvkstwJzX32iv9BTesBfLRlvpszyDNxBVRPyhFur~P3urrtVAVLE7BGD6CQk7MJjfCpSqvE0CA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of retinoic acid on DNA synthesis. Human B cells were isolated and stimulated with μ (37.5 μg/mL) and SAC (0.005%) as described in Material and Methods. Cells (0.75 × 106 cells/mL) were cultured in 96-well culture plates in triplicates. Retinoic acid (10 or 1000 nmol/L) was added at the indicated times (T) after stimulation. [3H]Thymidine incorporation (mean ± SD) was measured as described in Material and Methods. One representative experiment of three is shown. μ, F(ab′)2 fragment of rabbit antihuman IgM; SAC,Staphylococcus aureus crude cell suspension; RA, retinoic acid.
