Nucleotide sequence of the mvWF promoter. Alignment of the 5′ flanking region and first exon of the mouse, human, and bovine vWF genes. The numbers of the nucleotide sequence relative to the start site of transcription are on the right. The transcriptional start site is marked as +1. The TATA box is in bold. Potential consensus sites for DNA-binding proteins in the 5′ flanking region and first exon are underlined. The upper strand represents the mouse sequence (M), the middle strand the human sequence (H), and the lower strand the bovine sequence (B).