Growth of myeloma blood cells from patient no. 10 in SCID-hu host. SCID-hu host was inoculated with blood cells (containing 0.1% plasma cells) and with PC-depleted blood cells. (A) Human Ig levels. (•) Blood cells; (○) PC-depleted blood cells; (▪) host inoculated with bone marrow cells containing 11% myeloma plasma cells. (B) Flow cytometry dot plot of CD38CD45 profile of the blood cells. The sort window excluding CD45⁻ and CD45⁺plasma cells is shown. (C and D) X-radiograms of host injected with blood cells (C) and with PC-depleted blood cells (D). Note severe decalcification of myelomatous human bone in (C).