Phenotypic characterization of autologous antileukemia T-cell lines generated from the bone marrow of patients with B-cell precursor ALL. The histograms shown are from 2 representative patients (of 10 studied). Open areas represent fluorescence distribution of the MoAbs tested and solid areas represent that of isotype-matched control antibodies. The cell number is shown on the y-axis. The expression of these molecules was CD45RO (72% to 95%), CD40L (12% to 47%), CD26 (36% to 70%), 4-1BB/CD137 (59% to 86%), CD100 (68% to 97%), and CD95 (73% to 100%). These autologous antileukemia T-cell lines produce both T_H1- and T_H2-type cytokines (data not shown).