Fig. 4.
![Fig. 4. Effect of the MEK inhibitor on DNA synthesis capacity of CD34+ cells grown with rhuMGDF. Cells from cultures performed in the absence (▪) or presence (▨) of 6 μmol/L PD98059 were harvested at the indicated days and DNA synthesis was assessed by measuring [3H]thymidine incorporation. Results are mean ± SD of triplicate determinations from a representative experiment of 3 performed. The relative increase in [3H]thymidine incorporation in PD98059-treated cells as compared with control DMSO-treated cells is indicated below the bars for each time point.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/94/5/10.1182_blood.v94.5.1601/5/blod41719004x.jpeg?Expires=1735534445&Signature=0Oj5tCXOXoedgOKPPntj5GF1yio5IrW1BLBCjBf6z07xbhQyBfaq6vW0zAmf41zlYUYw7oEK40mQTtQZTtDOtL56Yv4VgZBrDlVuYVH45ahllCu24kVNUWtKgHqg2eVg3Uyi4PUkOg102Pxw~3VBCVRilu8mTSVf5t355iE2ARTRHMIUspHK8yKPq4a4M8u1K-lJlDzK56QFId2TEO-WEb~JS5pmx2WrYj1InEQ0iPfIroMwud7zX-phHEdtPk3SGN7IGhcIC8EOUVPRyLy6NoDvWSu7D4GJrAXaUiSmTZx3beqBqaOjgb5TCpr2nheJzWGITIGWur9imgPMVH5bWg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of the MEK inhibitor on DNA synthesis capacity of CD34+ cells grown with rhuMGDF. Cells from cultures performed in the absence (▪) or presence (▨) of 6 μmol/L PD98059 were harvested at the indicated days and DNA synthesis was assessed by measuring [3H]thymidine incorporation. Results are mean ± SD of triplicate determinations from a representative experiment of 3 performed. The relative increase in [3H]thymidine incorporation in PD98059-treated cells as compared with control DMSO-treated cells is indicated below the bars for each time point.
