Fig. 7.
Effect of antioxidants on SA-induced eosinophil apoptosis. Eosinophils were coincubated for 19 hours with SA (50 μmol/L) and GSH (○), NAC (▪), or TAUR (▾) at the indicated concentrations. Data are presented as mean ± SEM of 11 separate experiments. NAC more than GSH inhibited SA-mediated eosinophil apoptosis. Optimal concentration of GSH and NAC were 10 mmol/L each. In contrast, TAUR and DMSO (not shown) showed no effect on SA-mediated eosinophil apoptosis. *P < .05, **P < .01, ***P < .001 versus control (without stimulus).