Promoter activity of the 5′ region of the EphA3 gene and various deletion mutants. On the bottom is a schematic representation of the EphA3 gene 5′ region. The various genomic fragments were cloned as PCR products 5′ to the luciferase reporter. The numbering is relative to the transcription initiation site (0). Luciferase activities of each transfected construct were normalized to β-galactosidase activities. Each transfection was assayed at least 3 times and the mean values are shown on the graph (error bars indicate sample standard deviation).