Antibody-redirected cytolytic activity of freshly isolated splenocytes and in vivo–generated CTL. In vivo-generated CTL (A) and freshly isolated nonadherent splenocytes injected (B) from WT (left panels) and Tg-KIR2DL3 mice (right panels) were tested in a redirected killing assay against P815 target cells at an E:T ratio of 5:1 for the CTL and 200:1 for the splenocytes. (▪) Anti-CD3; (□) anti-CD3 + anti-KIR2DL3.