Proliferative response of HEL-primed Tg-HLA-Cw3, Tg-KIR2DL3, and Tg-KIR2DL3 × HLA-Cw3 mice lymph node cells. Tg-HLA-Cw3 (•), Tg-KIR2DL3 (▪), and Tg-KIR2DL3 × HLA-Cw3 (▴) mice were immunized with HEL, and the draining lymph node cells were isolated 9 days after the immunization. Lymph node cells were then restimulated in vitro in the presence of the indicated concentrations of HEL and cell proliferation was measured after 4 days of culture. Data shown are representative of 3 independent experiments.