Fig. 4.
![Fig. 4. Proliferative responses of thymocytes from Jak3+/+ mice (+/+), control-treated Jak3−/− mice (−/−), and IL-3–treated Jak3−/− littermates (−/− IL-3). Jak3−/− thymocytes do not respond to T-cell mitogenic and Jak3-dependent cytokine stimuli. Thymocytes were stimulated with mitogen/cytokine combinations as described in Materials and Methods, and their proliferation was measured by incorporation of [3H]-thymidine. Values are average stimulation indices ± SD (n = 2 in each group).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/94/6/10.1182_blood.v94.6.1906/5/blod41832004x.jpeg?Expires=1735828154&Signature=W7BViFz-0APXvuP4SH8iHXFGOsPhIGwxhW35b0OzPUcgNkiX7WzwbndBRMmLP~Uk7KcB0mi1CjAJYAGa58FaubNYZ8-PJbN8uwftT5wOpsKMh0dtRU4KEgQfccsZLsPRrgCbKp~-IHT1M3GKpDqEnotsLEbkzGUNHQY4zocxtGGt3oMuVt8Y~ehQaxGgpYBdQ3O5SCLhbnE9cOLU653edlmUN9eHpyUQqwVYl4iShaZOTT6wqFM6Q1WZa2FeKBnBUFqk4-OzBATpoYztNfh8Pog6r~Z-sRantqyd66sVMUEC6qwrQO3a0Lwg0rT7JONYT0f6VSGMWdu5wM0xgFAFyg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Proliferative responses of thymocytes from Jak3+/+ mice (+/+), control-treated Jak3−/− mice (−/−), and IL-3–treated Jak3−/− littermates (−/− IL-3). Jak3−/− thymocytes do not respond to T-cell mitogenic and Jak3-dependent cytokine stimuli. Thymocytes were stimulated with mitogen/cytokine combinations as described in Materials and Methods, and their proliferation was measured by incorporation of [3H]-thymidine. Values are average stimulation indices ± SD (n = 2 in each group).
