Fig. 1.
Comparison of the amino acid sequence of the C-terminus (residues 183-208) of M-Ras and a C elegans orthologue of M-Ras (Ce) with R-Ras, R-Ras2, H-, N-, and K-RasA/B. All sequences are murine with the exception of R-Ras2 (human). Gaps are indicated by a hyphen (-). The CAAX-motifs are boxed. Shaded areas indicate regions of homology between M-Ras and its C elegans orthologue (dark gray), the proline-rich R-Ras box (medium gray), and conserved regions in H-Ras, N-Ras, and K-RasA (light gray). Poly-lysine motifs in M-Ras and K-RasB are underlined. Cysteine residues that might be palmitoylated are double underlined. C eleganssequence accession no. is CE00958.