(A) Photograph of a malignant PC with t(4;14) and deletion 13q. The 4p16 (FGFR3) probe is labeled in red, whereas the 14q32 probes (Ig10 and 158A2) are labeled in green and the 13q32 probe in white/grey. The t(4;14) is represented by the fusion signal and the normal chromosomes 4 and 14 by the red and green signals, respectively. Only 1 white signal is observed, reflecting deletion 13q. (B) A plasma cell of a patient with t(8;14)(q24;q32). The translocation is identified by the fusion of 1 green (14q32 probe) and 1 red (8q24) signal. The separated green and red signals correspond to the normal chromosomes 14 and 8, respectively. Finally, this patient did not display chromosome 13 monosomy, because 2 white signals (13q32 probe) were observed. (C) Translocation t(11;14)(q13;q32), not associated with monosomy 13, in a patient with multiple myeloma. The fusion of 1 green (14q32 probe) and 1 red (11q13 probe) signal corresponds to the derivative chromosome 14, whereas the separated green and red signals represent normal chromosomes 14 and 11, respectively. Two white signals (13q32 probe) are observed.