Fig. 4.
Reconstitution of IEL in γc-deficient mice that received γc-transduced bone marrow. Paraffin sections of small intestinal tissue were stained with hematoxylin and eosin and evaluated for the presence of IEL by light microscopy (40×). wt, wild-type mouse; γcKO, γc-deficient mouse that received no treatment; γcKO-mock, γc-deficient mouse that received mock-transduced γc-deficient bone marrow; γcKO-wt, γc-deficient mouse that received wild-type bone marrow; γcKO-hγc, γc-deficient mouse that received γc-deficient bone marrow transduced with human γc. Sections shown are representative of results from 2 separate experiments. Arrows indicate IEL in the wt, γcKO-wt, and γcKO-hγc mice.
