Fig. 2.
Circulating corticosterone levels in fetuses either from adrenalectomized pregnant rats (Adx), control, Sham rats (Sham), and adrenalectomized pregnant rats provided with corticosterone (Adx+GCs). To reconstitute the corticosterone serum levels in the Adx-fetuses, 1 osmotic minipump (2ML4, ALZET, Alza Corporation) was subcutaneously implanted in pregnant rats during adrenalectomy surgery procedure, which regularly infused 23 μg/hour of corticosterone. Data represent the average values of 3 to 4 experiments ± standard deviation (SD). Significant differences to Sham fetuses are marked as*P ≤ .05; ** P ≤ .01,*** P ≤ .001.