Fig. 6.
Proportion of PIGA(−) cells in peripheral blood from mosaic mice. (A) Proportion of PIGA(−) RBCs during the observation period of 12 months. (B) Proportion of PIGA(−) granulocytes (PMN), T cells, B cells, CD8+, and CD4+ cells during the observation period of 12 months. Each box plot displays the 10th, 25th, 50th, 75th, and 90th percentile. Values above the 90th or below the 10th percentile are plotted [Table 2 shows the values for median, the number of animals analyzed, and the level of significance of the difference in the percentage of PIGA(−) cells between 2 successive time points]. (C) Proportion of PIGA(−) reticulocytes in relation to the proportion of PIGA(−) RBCs, granulocytes (PMN), and lymphocytes (Lyc) in 11 animals more than 16 weeks of age. The values for the median are indicated and shown by a horizontal line.