Fig. 3.
Aspirin-triggered LXA4 analog (15-R/S-methyl-LXA4) inhibits PAF-induced changes in cell surface expression of L-selectin and CD18 by human neutrophils. Whole blood was incubated in medium only (unstimulated) or with 15-R/S-methyl-LXA4 (5 μmol/L) for 10 minutes and then with PAF (1 μmol/L) for 30 minutes at 37°C. In each histogram is also displayed the negative control of immunostaining with class-matched irrelevant antibodies (C). Shown is a representative experiment of 5 experiments.
