Fig. 3.
Membrane topology of some variant D proteins associated with partial D phenotypes. The serological reactivity of the mutant K562 cell lines was compared with that of some naturally occurring partial D phenotype red cells. These phenotypes are predominantly associated with hybrid Rh proteins. The predicted structures of these hybrids are depicted: RHCE-derived amino acids are shown as open circles, whereas RHD-derived amino acids as shown as solid circles. The molecular bases of the different partial D phenotypes shown have been described previously: DIVa; DIVb and DFR24; DBT20; RoHar19; and cDVIE.17
