Fig. 2.
Representative examples of deviated and normal TCR CDR3 size distributions. (A) Analysis of CDR3 size distribution patterns in UPN 272 at 3 months after allo-BMT in CD4+ and CD8+ T-cell subsets as an example of a deviated/less heterogenous distribution of TCR CDR3 sizes. (B) Similar analysis in UPN 301 at 3 months after allo-BMT in CD4+ and CD8+ T-cell subsets as an example of a less heterogenous/Gaussian distribution of TCR CDR3 sizes. (C) UPN 301 at 1 year after allo-BMT in CD4+ and CD8+ T-cell subsets as an example of a Gaussian distribution of TCR CDR3 sizes. Lanes indicate from left to right TCRBV families (1 through 23).