Quantitative analysis of bronchoalveolar lavage eosinophils in IL-1 R type 1-deficient mice.

The number of eosinophils in bronchoalveolar lavage (BAL) fluid was enumerated before and after allergen challenge and after diluent challenge in wild-type (WT) and IL-1 R type 1-deficient (IL-1 R I KO) mice. Results are expressed as the percentage of eosinophils in BAL fluid (n = 3 experiments). There was a significant inhibition of BAL eosinophilia in IL-1 R type 1-deficient mice after allergen challenge compared with wild-type mice after allergen challenge (P = .001).