Fig. 2.
Effect of PAI-1 and VN deficiency on venous thrombosis.
The internal jugular veins of WT, PAI-1-deficient, and VN-deficient mice were continuously monitored for flow following photochemical injury to the internal jugular vein. The average time to occlusive thrombosis was longer in mice deficient in PAI-1 and in mice deficient in VN compared with WT mice. *P < .04 compared with WT; **P < .01 compared with WT mice.