Platelet numbers in double mutant mice.

Platelet counts in wild-type (wt) mice and mice lacking c-mpl, LIF, IL-6, IL-11 receptor alpha chain (IL-11Rα), or combinations of these regulators are shown. The means ± SD were determined from measurements from 3 to 9 mice per genotype. No statistically significant differences were observed (P > .05, Studentt test) for comparison of data from LIF^-/-, IL-6^-/-, or IL-11Rα^-/- mice with wild-type controls or of LIF^-/-mpl^-/-, IL-6^-/-mpl^-/-, or IL-11Rα^-/-mpl^-/-mice withmpl^-/- data.