Fig. 4.
Both lymphoid and myeloid cells exhibit EGFP fluorescence in mice engrafted with marked SRC.
(A) NOD/SCID marrow cells labeled with anti-CD45-PerCP and anti-CD19-PE and analyzed by flow cytometry; region R1 defines the CD45+CD19+ human B lymphocyte population. (B) NOD/SCID marrow cells labeled with anti-CD45-PerCP and anti-CD33-PE; region R2 defines the CD45+CD33+ human myelocyte population. (C) EGFP fluorescence is detected within human B lymphocytes using the R1 gate in (A). (D) EGFP fluorescence is detected within human myelocytes using the R2 gate in (B).