Fig. 2.
Flow cytometric analysis of Ph1-ALL cells purified according to their distribution of CD34 and CD38 expression.
Cells from PBLs of patient No. 2 were analyzed by flow cytometry. The blast lymphoid gated cell population was then analyzed for CD34 and CD38 expression. Circles containing cells that express CD34++CD38− and CD34+CD38+ cells were chosen as the sorting region. These cells, fractionated into pure CD34++CD38− and CD34+CD38+ subgroups, were transplanted into NOD/SCID mice.