Deletions detectable by microsatellite PCR in bone marrow and peripheral blood granulocytes.

Microsatellite PCR was performed on samples from 3 different Ph-positive patients by using primers for the loci indicated below each panel. BM indicates bone marrow; G, granulocytes; and T, T cells. (A) Loss of heterozygosity at the ASS locus in bone marrow from patient 5. (B) Loss of heterozygosity at the D9S159 locus in peripheral blood granulocytes from patient 3. (C) No loss of heterozygosity at the D9S159 locus in granulocytes from a patient with no detectable deletion.