Fig. 1.
![Fig. 1. MLL is fused in-frame to the AF3p21 in the t(3,11) (A) Genomic sequences of the MLL,MLL-AF3p21 (derived from the derivative chromosome 11[der(11)]), and AF3p21 genes at the breakpoint region. / (B) Sequence of the der11 MLL-AF3p21 fusion junction amplified by RT-PCR. (C) Schematic diagram of the consequences of the MLL, MLL-AF3p21, and AF3p21 proteins.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/95/3/10.1182_blood.v95.3.1066.003k11_1066_1068/6/bloo0031101z.jpeg?Expires=1735550544&Signature=x-8Ow190LclUStqA67oEmwcHi7XizFJN6PGTLFi4Fees5FR-MQUEEwCUQf7dX2KJa-OgGmm1LOS7wgtewCDVwGgA3ZmJBXjzJ1T2xNmB-TUvTSf2qQpzPFFYHPDWo4r2vVkcuDNlBuP4HIKW5ui~hBMzPSq8vRFFilqsRgmlpA69ya3bObGNC-g4Y3BvnCrCwGKrBIIf5BsYLr7a3QI4ZOEvtZBGWwhm1kf-fG01A~~nHjczWenxlvKEp9tfNBv4X8zfhO5CH4vLSK~e2WMmn6brp~0Mt-wAOD1cn70PeV~ROu4r-qEI0OgbOh2SExDM1ORcOXV4RyZaMhsmKwCvlA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
MLL is fused in-frame to the AF3p21 in the t(3,11) (A) Genomic sequences of the MLL,MLL-AF3p21 (derived from the derivative chromosome 11[der(11)]), and AF3p21 genes at the breakpoint region.
(B) Sequence of the der11 MLL-AF3p21 fusion junction amplified by RT-PCR. (C) Schematic diagram of the consequences of the MLL, MLL-AF3p21, and AF3p21 proteins.
