Fig. 4.
Decrease of spontaneous apoptosis in primary myeloma cells by IL-15 treatment.
The mononuclear fractions of bone marrow samples of 14 myeloma patients were cultured without or with IL-15 (10 ng/mL) for 24 hours. The percentages of apoptotic cells in the CD38high/CD45low subpopulations were determined by the annexinV/FITC/PI assay. The significance of IL-15 treatment was analyzed using the paired Student t test.