Fig. 1.
The BM and a vertebral mass from MM-engrafted mice includes human CD38hi plasma cells.
Mouse BM was removed from the femurs, the red cells lysed, and the remaining cells stained with CD38 and CD19 mAbs in 2-color immunfluoresence. Representative dot plots from 3 different mice and from 1 vertebral tumor are shown. No CD38hi cells were detected in uninjected control mice (not shown).