Survival of BALB/c recipients given BCL-1 leukemia/lymphoma cells.
BALB/c mice were injected intraperitoneally with 10 × 106 BCL1 cells from BALB/c leukemic donors. Twenty-four hours later, they were lethally (8 Gy) irradiated, then injected intravenously with B10D2 bone marrow cells (2.5 × 106) or bone marrow cells (2.5 × 106) plus spleen cells (10 × 106). These BCL1-bearing recipients were divided into 3 groups. Group A (n = 10) BCL1-bearing recipients received bone marrow cells alone. Group B (n = 10) BCL1-bearing recipients received bone marrow plus spleen cells. Group C (n = 10) BCL1-bearing recipients received bone marrow plus spleen cells and PG27 for the first 35 days after transplantation. Data are pooled from 2 similar experiments.
