CXCR3 and Mig expression in low-grade B-cell lymphomas.

(A) Immunohistochemical detection on paraffin-embedded and cryostat sections using the 1C6/CXCR3 and 4G10/Mig monoclonal antibodies. Abbreviations: H&E, hematoxylin and eosin staining; CLL, nodal involvement by B-cell chronic lymphocytic leukemia; MCL, mantle cell lymphoma; FL, follicular lymphoma; SMZL, splenic marginal zone lymphoma. (B) Flow cytometric detection of CXCR3 in a representative case of B-CLL (3-color CD19/CD5/CXCR3 staining in panels 1 and 2) and mantle cell lymphoma (panel 3). Cytograms represent all cells in the sample within the lymphocyte gate.