The effect of PAF on the hemodynamic behavior of AA and SS RBC in the ex vivo mesocecum vasculature.

In untreated (control) preparations, SS RBC (n = 4) resulted in a 1.6-fold increase in the PRU compared with AA RBC (P < .002). In PAF (200 pg/mL)-treated preparations, SS RBCs caused a 1.6-fold increase in PRU compared with SS RBC infusions from the same patients in untreated preparations (P < .025, pairedt-test). In contrast, PAF had no effect on PRU for AA RBC.