Fig. 5.
The effect of MoAb 7E3 F(ab′)2 on hemodynamic behavior of SS RBC in PAF-treated ex vivo mesocecum vasculature.
In preparations treated with OC125 F(ab′)2 (control antibody) or 10E5 F(ab′)2, SS RBC resulted in a comparable increase in the PRU as observed in the PAF-treated preparations (see Figure 1). In contrast, when the preparation was treated with MoAb 7E3 and PAF, SS RBC resulted in a significantly lower PRU compared with either control or 10E5.
