Fig. 1.
Induction of C-susceptibility by L. intermediavenom toxins.
(A) C-dependent hemolysis of E after incubation with VBS2+(C), with 10 μg/mL of L. intermedia venom (V), or with purified toxin P1, P2, or P3. (B) C3b deposition after treatment of E, followed by incubation with C8-depleted serum. Deposition was measured using polyclonal sera against C3 and analysis by flow cytometry. Results are representative of 3 different experiments carried out in duplicate and represented as mean ± SD.
