Family pedigrees of the 2 probands with congenital afibrinogenemia analyzed in this study.

(A) Pedigree of the Italian and (B) of the Iranian family. Plasma functional fibrinogen levels (mg/dL), immunoreactive fibrinogen levels (mg/dL), intraplatelet levels (μg/10⁹ platelets) and haplotypes of the FGA-i3 tetranucleotide repeat marker (alleles numbered from the largest to the smallest) are indicated in this order below each symbol. Arrows indicate the probands. nd, not done.