Influence of Exodus subfamily of CC chemokines on colony formation of progenitors in marrow from patients with CML.

Data are presented as the percentage of inhibition compared with control colony formation (without chemokine treatment) for each patient. Mean (± SD) control colonies were 69 ± 83 for CFU-GM, 85 ± 55 for BFU-E, and 35 ± 36 for CFU-GEMM. For the CML patient samples, data are presented as average values, with SD bars. If no SD bars are shown, the SD was too small to be included on the figure. For Exodus-1, n = 13; for Exodus-2, n = 4; for Exodus-3, n = 3; and for MIP-1α, n = 11. Two CML patient samples in which MIP-1α inhibited the progenitors are not on the figure but are discussed in the text.