Dose response to interleukin 3 of mast cell DNA synthesis.

Protein kinase C (PKC) β-deficient and wild-type mast cells were incubated for 24 hours with medium containing increasing doses of interleukin 3 (IL-3) and then with tritium-thymidine for 4 hours. The level of incorporation of radioactivity into DNA (mean ± SE) was quantified for each condition in quadruplicate. One representative experiment of 3 is shown.