Fig. 1.
rAAV/BDD-hFVIII constructs.
The maps for the 2 rAAV constructs expressing BDD-hFVIII are shown: pDLZ2 (4965 bp including 2 ITRs, 107% of wt-AAV) and pDLZ6 (5089 bp including 2 ITRs, 109% of wt-AAV). ITR, AAV inverted terminal repeat; EnhI, Enhancer I of the HBV; Ptk, TK promoter of the HSV; and P(A), herpes simplex thymidine kinase polyadenylation sequence.