Increase of p24 Ag release by Th1-polarized naive CD4⁺ T cells infected with HIV-1BaL in the presence of anti-RANTES, anti-MIP-1, and anti-MIP-1β neutralizing mAbs.

Th1-polarized (black columns) and Th2-polarized (open columns) CD4⁺–activated naive T cells were infected with HIV-1BaL in the presence of a mixture of anti-RANTES, anti-MIP-1α, and anti-MIP-1β or of isotype-matched control mAbs. Values are expressed as the percent of p24 Ag released in the presence of antichemokine mAbs versus the percent of p24 Ag released in the presence of control mAbs. Columns represent mean values ± SE of 9 separate experiments.