Right panel. Carbonylcyanide-m-chloro-phenyl-hydrazone–mediated pH traces (left axis) and corresponding membrane potentials (right axis) from suspensions of normal erythrocytes (A/A) showing the increasing hyperpolarization due to inhibition of the chloride conductance with increasing concentrations of NS1652 (0, 1.0, 3.3, 10, and 20 μM) under standard experimental conditions.

The valinomycin concentration was 10⁻⁷ mol/L. All experiments were stopped by addition of Triton-X-100 to determine the pH_i and thereby the corresponding zero membrane potential. Left panel: Chemical structure of NS1652.