Fig. 1.
Fig. 1. The role of B7-1 and B7-2 antigens in the antifactor VIII antibody response. / Hemophilia A/B7-1−/− (○) and hemophilia A/B7-2−/− (•) mice were injected intravenously with 0.2 μg factor VIII at 2-week intervals. Serum samples for antifactor VIII assay were obtained 12 days after the second and sixth factor VIII injections.

The role of B7-1 and B7-2 antigens in the antifactor VIII antibody response.

Hemophilia A/B7-1−/− (○) and hemophilia A/B7-2−/− (•) mice were injected intravenously with 0.2 μg factor VIII at 2-week intervals. Serum samples for antifactor VIII assay were obtained 12 days after the second and sixth factor VIII injections.

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