American Society of Hematology

Fig. 1.

$Fig. 1. Leukotriene A4 metabolism in CML and normal granulocytes. / Unfractionated granulocyte suspensions (15 × 106cells/mL) from CML patients and healthy controls were incubated with LTA4 (10 μmol/L) at 37°C for 5 minutes. Levels of LTC4 and LTB4 were determined by HPLC. Each value represents the mean obtained from duplicate experiments with cells from 13 CML patients and 11 healthy controls. Error bars indicate SEM. ***Indicates P < .001.$

Leukotriene A₄ metabolism in CML and normal granulocytes.

Unfractionated granulocyte suspensions (15 × 10⁶cells/mL) from CML patients and healthy controls were incubated with LTA₄ (10 μmol/L) at 37°C for 5 minutes. Levels of LTC₄ and LTB₄ were determined by HPLC. Each value represents the mean obtained from duplicate experiments with cells from 13 CML patients and 11 healthy controls. Error bars indicate SEM. ***Indicates P < .001.

This Feature Is Available To Subscribers Only