Actin polymerization in WAS, XLT, and control lymphocytes isolated 24 hours after venipuncture.

Actin cytoskeletal remodeling in response to stimulation with 100 nmol/L PMA or buffer (▪) in WAS (•), XLT (⧫), and control (▴) lymphocytes isolated from whole blood incubated at room temperature for 24 hours after venipuncture. Aliquots of cells were removed and analyzed for F-actin content at the indicated times. Error bars reflect SEM of duplicate simultaneous determinations from 1 donor (control or WAS). The graph is representative of data collected from 2 patients with WAS, 3 patients with XLT, and 5 control donors.