Dose effect of PDGF-BB or FGF-2 on TPO mRNA expression in BM stromal cells.

The levels of TPO mRNA expression in the BM stromal cell cultures were measured 4 hours after treatment with increasing concentrations of PDGF (A) or FGF (C). GAPDH mRNA levels remained unchanged in cells exposed to PDGF (B) or FGF (D). The results shown are the mean ± SD values from 5 separate experiments carried out in triplicate. *P < .05 compared with controls.